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Relationship between carcinogenesis of esophageal squamous cell carcinoma and esophageal microbiota

Relationship between carcinogenesis of esophageal squamous cell carcinoma and esophageal microbiota - Relationship between carcinogenesis of esophageal squamous cell carcinoma and esophageal microbiota

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000033544
Enrollment
35
Registered
2018-07-30
Start date
2018-07-30
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal squamous cell carcinoma and achalasia

Interventions

None listed

Sponsors

Graduate School of Medical and Dental Sciences, Niigata University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient who is older than 18 when the informed consent is obtained. 2. The patient who is diagnosed with achalasia or esophageal squamous cell carcinoma and is going to undergo endoscopic treatment in our hospital. 3. The performance status of the patients is 0, 1, or 2. 4. The patient whose informed consent is obtained.

Exclusion criteria

Exclusion criteria: 1. The patient who is pregnant or performing breast feeding. 2. The patient who was registered in this study before. 3. The patient who has risks for bleeding after esophageal biopsy. 4. The patient who underwent gastrectomy before. 5. The patient who had past histories of cervical cancer or esophageal cancer treated by radiation. 6. The patient who are being treated for cancers in other organs 7. The patients who are judged by the investigators to be inappropriate participants in the trial.

Design outcomes

Primary

MeasureTime frame
The effect of esophageal microbiota on carcinogenesis of esophageal squamous cell carcinoma in patients with achalasia

Secondary

MeasureTime frame
Esophageal microbiota before and after per-oral endoscopic myotomy in patients with achalasia. Comparison of esophageal microbiota between the patients with esophageal squamous cell carcinoma and the patients with achalasia

Countries

Japan

Contacts

Public ContactKazuya Takahashi

Graduate School of Medical and Dental Sciences, Niigata University Division of Gastroenterology and Hepatology

kazuya911@med.niigata-u.ac.jp025-227-2207

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026