Sepsis
Conditions
Interventions
The intervention group will receive EMS as follows. Belt electrodes of the Auto Tens Pro (Homer Ion Co. Ltd., Tokyo, Japan) will be placed around the abdomen, distal part of both thighs, and both ankl
Sponsors
Center Hospital of the National Center for Global Health and Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.A signed informed consent form for participation in the study provided by the patient, or if difficult, by an authorized representative who has the legal capacity to decide the therapy strategy. 2.=> 20 years old 3.Diagnosis of sepsis
Exclusion criteria
Exclusion criteria: 1.Presence of a pacemaker 2.Known primary systemic neuromuscular disease or intracranial disease at admission 3.Pre-hospitalization functional independence measure (FIM) score < 80, with inability to walk independently 4.Fracture or skin lesion (except contusion) in the region subjected to EMS (thigh, knee joint, ankle joint) 5.Pregnancy 6.Assessed as approaching or imminent death 7.Trauma 8.Unable to reach consensus 9.Determined by the physician-in-charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is decrement in quadriceps strength (N/kg) on Day 15 versus Day 1. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are decrements in muscle strength grade determined by the manual muscle test (MMT) and in thickness of the rectus femoris muscle on Day 1, Day 8, and Day 15. The pre-hospitalization FIM score will be recorded on the day of hospital admission, and change in the FIM score on Day 15 compared with the prehospitalization value will be assessed | — |
Countries
Japan
Contacts
Public ContactKento Takii
Center Hospital of the National Center for Global Health and Medicine Department of Emergency Medicine and Critical Care
Outcome results
None listed