Healthy subjects
Conditions
Interventions
Low gamma PGA natto. 40g per day for 6weeks.
High gamma PGA natto. 40g per day for 6weeks.
Sponsors
Fuculty of Medicine University of Tsukuba
1.Takanofoods Co.,Ltd. 2.Industrial technology innovation center of Ibaraki prefecture. 3.National agriculture and food research organization, food research institute.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.BMI not less than 23.0 kg/m2, under 25.0 kg/m2 2. Capable of giving informed consent.
Exclusion criteria
Exclusion criteria: 1. Fasting blood glucose not less than 126 mg/dL and/or HbA1c not less than 6.5% 2. TG not less than 200 mg/dL and/or LDL-C not less than 160 mg/dL 3. SBP not less than 160 mmHg and/or DBP not less than 100 mmHg 4. Subjects who are treated for diabetes and/or hyperlipidemia and/or hypertension. 5. Subjects who are habitually taking supplement (including "food for specified health use", and "foods with function claims") that include lactic acid bacterium, bifidobacteria, oligosaccharide, dietary fiber, and ingredients of natto. 6. Subjects who are enrollment in another interventional study 7. Subjects who were recognized unsuitable for this study by the Investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood lipid level(TG, HDL-C, LDL-C, TC) at 12 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Body weight, Waist circumference 2.Blood pressure 3.Biomarkers(fasting blood gulcose, HbA1c, insulin, C-peptide, AST, ALT, amma GTP, BUN, Cr, UA, FFA, TP, Alb) 4.Amount of test meal consumption 5.Defecation frequency 6.Organoleptic evaluation | — |
Countries
Japan
Contacts
Public ContactKoichi Hashimoto
University of Tsukuba, Faculty of Medicene Clinical and Translational Research Methodology
Outcome results
None listed