The possibility of IL-36 cytokines as a novel biomarker of the severity and mortality in the patients with bacteremia or sepsis.

The possibility of IL-36 cytokines as a novel biomarker of the severity and mortality in the patients with bacteremia or sepsis. - The role of IL-36 cytokines in sepsis.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033513

Enrollment

100

Registered

2018-07-25

Start date

2018-07-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacteremia and Sepsis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) The patients who are hospitalized with bacteremia or sepsis at department of emergency room at Tohoku university hospital. (2) The patients who are over 20 years old. Informed consent are obtained from the patients themselves and their relatives if we can not obtain informed consent from the patients with severe condition. (3) Gender: not applicable (4) Healthy volunteers - over 20 years old - gender: not applicable - who can obtain informed consent

Exclusion criteria

Exclusion criteria: (1) The person who are under 20 years old (2) Pregnancy (3) The person whom we can not obtain the informed consent. (4) Not appropriate as a physician's judgement

Design outcomes

Primary

Measure	Time frame
The production of IL-36 cytokines Severity and mortality	—

Secondary

Measure	Time frame
Extracellular microvesicles	—

Countries

Japan

Contacts

Public ContactTetuji Aoyagi

Tohoku University Department of Infectious Diseases

tetsujiaoyagi@med.tohoku.ac.jp0227177373

Outcome results