The effects of improvement of function of high density lipoprotein cholesterol, endothelial function, and suppressioun of oxidative stress by lycopene supplement after cardiac rehabilitation.

The effects of improvement of function of high density lipoprotein cholesterol, endothelial function, and suppressioun of oxidative stress by lycopene supplement after cardiac rehabilitation. - The effects of lycopene supplement after cardiac rehabilitation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033505

Enrollment

Registered

2018-07-30

Start date

2018-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease

Interventions

Group which intakes lycopene supplement at one dose per day during 3 months Group which does not intake lycopene supplement during 3 months

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who suffered from cardiovascular diseases, has visited cardiac rehabilitation at least once a week in Fukuoka university hospital, is less daily lycopene intake by food than determined amount, and does not have an allergy of soy or gelatin which is component of lycopene supplement are included.

Exclusion criteria

Exclusion criteria: The patients who intakes lycopene a lot or has an allergy of soy or gelatin are excluded.

Design outcomes

Primary

Measure	Time frame
Efflux capacity of high density lipoprotein after 3 months intake	—

Secondary

Measure	Time frame
Superoxide dismutase activity, thiobarbituric acid reactive substance, lipid profile, BNP, NT-pro BNP, muscle volume, muscular strength, endothelial function by FMD, vessel function by PASESA and nico, exercise tolerance by CPX, physical activities after 3 months intake	—

Countries

Japan

Contacts

Public ContactYasunori Suematsu

Fukuoka University Cardiology

ysuematsu@fukuoka-u.ac.jp092-801-1011

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026