Detection of pancreatic beta cell DNA in the circulation of patients with type 1 diabetes using the dual Amplification Refractory Mutation System PCR

Detection of pancreatic beta cell DNA in the circulation of patients with type 1 diabetes using the dual Amplification Refractory Mutation System PCR - Detection of pancreatic beta cell DNA in the circulation using the dual Amplification Refractory Mutation System PCR

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033501

Enrollment

370

Registered

2019-03-31

Start date

2018-08-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 1 diabetes, pancreas transplantation, islet transplantation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with type 1 diabetes, person with familial history of type 1 diabetes, person who are suspects of type 1 diabetes, pancreas or islet transplanted patients, patients with type 2 diabetes, and healthy volunteer subjects.

Exclusion criteria

Exclusion criteria: Any condition which, in the opinion of the investigator, would compromise the ability to meet protocol requirements.

Design outcomes

Primary

Measure	Time frame
To develop a precise method for detecting pancreatic beta cell DNA in the circulation in 370 patients with type 1 diabetes, pancreas or islet transplanted patients.	—

Secondary

Measure	Time frame
The comparison between beta cell DNA positive patients and their clinical characteristics.	—

Countries

Japan

Contacts

Public ContactAkio Kuroda

Institute of Advanced Medical Sciences, Tokushima University Diabetes Therapeutics and Research Center

kurodaakio@tokushima-u.ac.jp088-633-7587

Outcome results