Skip to content

The effect of MCT oil on cognitive function and neural basis of the elderly

The effect of MCT oil on cognitive function and neural basis of the elderly - MCT SMILE project

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000033447
Enrollment
65
Registered
2018-07-23
Start date
2018-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Patients are asked to intake the MCT containing food, yogurt flavored jelly type one, for 3 months. MCT oil 15g/package, 6g MCT oil contained start with 1package/day and increase the dose if th

Sponsors

Tohoku University
Lead Sponsor
The Nisshin OilliO Group, Ltd. Kousei Sendai Clinic
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Cognitive healthy or mild cognitive impaired elderly people (2) Cognitivi function (both) Mini Mental State Examinaton (MMSE) 24points or more Clinical Dementia Rating (CDR) 0~0.5points (3) Performance Status:0-1 (4) Age: 60-80 years old (5) Male and Female (6) Right handed patient admitted to Tohoku University Hosipital from April 2018 on

Exclusion criteria

Exclusion criteria: (1) Severe past history of brain, psychologycal disease (2) Clinical hemophilic arthritis (3) Liver disease accompanying coagulopathy (4) Metalic implant (pace maker, coronaly stent, artificial joint, etc.) (5) Claustrophobia (6) Diabetes Mellitus (FBG<100 mg/dL) (7) Depression (8) Severe visual and hearing disturbance (9) Muscular disease (10) Excessive obesity/slimming (BMI <17, >30) (11) Kidney Disease (CCr <15 mL/min) (12) Problem with digention or metabolism (13) Psychotic dysorder (14) Do not (cannot) concent to this study (15) Who assessed as not suitable for this study by conducting doctors

Design outcomes

Primary

MeasureTime frame
3-month change in ADAS-Jcog score

Countries

Japan

Contacts

Public ContactTatsushi Mutoh

Depertment of nuclear medicine and Radiology IDAC, Tohoku University

tmutoh@tohoku.ac.jp022-717-8559

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026