Elucidation of individual difference factors in the pharmacokinetics and clinical effects of anticoagulants edoxaban and enoxasaparin

Elucidation of individual difference factors in the pharmacokinetics and clinical effects of anticoagulants edoxaban and enoxasaparin - Elucidation of individual difference factors in the pharmacokinetics and clinical effects of anticoagulants edoxaban and enoxasaparin

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033422

Enrollment

100

Registered

2018-07-30

Start date

2015-06-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial knee replacement surgery

Interventions

Edoxaban Enoxaparin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: undergoing knee replacement

Exclusion criteria

Exclusion criteria: Patients with a history of DVT and PTE. Patients with diseases with abnormal coagulability. Patient who can not obtain written informed consent. Patients contraindicated with edoxaban or enoxaparin. Patients taking warfarin.Other patients judged inappropriate by the attending physician.

Design outcomes

Primary

Measure	Time frame
Efficacy (presence of thrombus by CT imaging)	—

Secondary

Measure	Time frame
Safety (with subcutaneous bleeding)	—

Countries

Japan

Contacts

Public Contactshibata,soichi

Kitasato University, Kitasato Institute Hospital Pharmacy

shibasoh@insti.kitasato-u.ac.jp03-3444-6161

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026