fatty liver disease (exclude alcoholic hepatitis)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed as fatty liver 2. ALT >= 40 3. Aged over 20 years old and under 75 4. PS 0 - 1 (ECOG) 5. Patients who are able to provide written consent to participate in this research in person, follow instructions during participation in this research, and undergo protocol-specified physical examination and other examinations.
Exclusion criteria
Exclusion criteria: Decompensated cirrhosis, Affected malignant tumor in 2-years (exclude carcinoma in situ), heart and lung disease (NYHA > II), percutaneous coronary intervention in 6 month, proliferative diabetic retinopathy, diabetic patient using sulfonylurea / insulin, diabetic neuropathy, severe musculoskeletal impairment, gestation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of ALT comparing between before and after intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory data, Body composition analysis (BIA method), amount of physical exertion (activity meter), Specific Activity Scale, Athens Insomnia Scale. Concurrently, the efficacy of exercise is also studied in non-intervention group (the evaluation items are the same as above). | — |
Countries
Japan
Contacts
Takeda hospital Gastroenterology and hepatology