Healthy adults
Conditions
Interventions
Daily ingestion 9 g of quercetin-rich onion powder for 12 weeks.
Daily ingestion 9 g of quercetin-free onion powder for 12 weeks.
Sponsors
Hokkaido Information University
1. Food Research Institute, NARO 2. Hokkaido Agricultural Research Center, NARO
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects who fully understand significance, content and purpose of this study and who agree to participate in this study with a written informed consent. 2. Subjects whose BMI is >=23 kg/m2 and <30 kg/m2.
Exclusion criteria
Exclusion criteria: 1.Subjects who are under physician's advice, treatment, and/or medication for obese, and/or hypertension. 2.Subjects who suspected obesity. 3.Pacemaker or defibrillator users. 4.Subjects whose hospital systolic blood pressure is >=160 mmHg and/or hospital diastolic blood pressure is >=100 mmHg. 5.Subjects who have (or suspected) secondary hypertension such as renovascular hypertension, renal parenchymal hypertension, primary aldosteronism, Cushing's syndrome, hypothyroidism, hyperthyroidism, etc. 6.Subjects with serious cerebrovascular, cardiac, hepatic, renal, gastrointestinal diseases, and/or affected with infectious diseases requiring reports to the authorities. 7.Subjects with major surgical history relevant to the digestive system such as gastrectomy, gastrorrhaphy, enterectomy, etc. 8.Subjects with unusually high and/or low blood pressure and/or abnormal hematological data. 9.Subjects with severe anemia. 10.Pre- or post-menopausal women complaining of obvious physical changes. 11.Subjects who are at risk of having allergic reactions to drugs or foods especially based on onion. 12.Subjects who regularly take medicine, functional foods, and/or supplements which would affect BW and BFR. 13.Subjects who regularly take medicine, functional foods, and/or supplements which would affect blood pressure. 14.Heavy smokers, alcohol addicts or subjects with disordered lifestyle. 15.Subjects who donated either 400 ml whole blood within 16 weeks (women), 12 weeks (men), 200 ml whole blood within 4 weeks (men and women), or blood components within 2 weeks (men and women), prior to the current study. 16.Pregnant or lactating women or women who expect to be pregnant during this study. 17.Subjects who currently participate in other clinical trials, or participated within the last 4 weeks prior to the current study. 18.Any other medical and/or health reasons unfavorable to participation in the current study, as judged by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visceral fat area at 12 weeks after beginning the ingestion of test food. | — |
Secondary
| Measure | Time frame |
|---|---|
| total fat area, subcutaneous fat area, body weight, body mass index, body fat rate, abdominal circumference, hospital blood pressure, home blood pressure, TBARS, serum quercetin | — |
Countries
Japan
Contacts
Public ContactJun NISHIHIRA, M.D., Ph.D.
Hokkaido Information University Health Information Science Center
Outcome results
None listed