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Construction of an in vitro evaluation system for novel aldosterone production inhibitors using cells derived from aldosterone producing adenomas (Sample provision to Pharmaceutical Research Department, NISSAN CHEMICAL CO., LTD.)

Construction of an in vitro evaluation system for novel aldosterone production inhibitors using cells derived from aldosterone producing adenomas (Sample provision to Pharmaceutical Research Department, NISSAN CHEMICAL CO., LTD.) - Construction of an in vitro evaluation system for novel aldosterone production inhibitors using cells derived from aldosterone producing adenomas

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000033401
Enrollment
30
Registered
2018-08-03
Start date
2018-12-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aldosterone producing adenoma

Interventions

Discovered adrenal tissue is dispersed in a single cell and aldosterone producing cells are extracted. Measure the concentration of steroid containing aldosterone from the extracted cells to confirm t

Sponsors

Saitama Medical University International Medical Center
Lead Sponsor
Nissan Chemical Corporation Biological Research Laboratories
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: APA patients to be adrenalectomized

Exclusion criteria

Exclusion criteria: Patients who did not obtain consent

Design outcomes

Primary

MeasureTime frame
Discovered adrenal tissue is dispersed in a single cell and aldosterone producing cells are extracted. The extracted cells are seeded on a plate, cultured for a certain period of time, the culture supernatant is collected, and the concentration of steroid containing aldosterone is measured to confirm that they are aldosterone producing cells.—

Countries

Japan

Contacts

Public ContactKoshiro Nishimoto

Saitama Medical University International Medical Center UroOncology

k.nishimoto@keio.jp042-984-4111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026