aneurysmal subarachnoid hemorrhage
Conditions
Interventions
None listed
Sponsors
Mie University Graduate School of Medicine, Department of Neurosurgery
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Written informed consent 2. More than 20 years of age at onset 3. modified Rankin Scale 0-2 before onset 4. Subarachnoid hemorrhage (SAH) on computed tomography (CT) scans or lumbar puncture 5. Saccular aneurysm as the cause of SAH confirmed on digital subtraction angiography or CT angiography 6. Aneurysmal obliteration by clipping or coiling within 48 hours of onset
Exclusion criteria
Exclusion criteria: 1. Non-idiopathic saccular aneurysms including traumatic, dissecting, tumor-related, and inflammatory aneurysms 2. Aneurysm treatment by parent artery occlusion 3. Patients with procedure-related complications 4. Severe systemic complications limiting routine post-operative managements 5. Diseases that potentially affect matricellular protein levels 6. Patients who are judged as being inappropriate by attending neurosurgeons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-month outcome Delayed cerebral infarction | — |
Secondary
| Measure | Time frame |
|---|---|
| Matricellular protein levels in blood at days 1-3, 4-6, 7-9, and 10-12 Early brain injury Cerebral vasospasm Delayed cerebral ischemia Chronic hydrocephalus | — |
Countries
Japan
Contacts
Public ContactHidenori Suzuki
Mie University Graduate School of Medicine, Department of Neurosurgery
Outcome results
None listed