Mechanical In-Exsufflation for the prevention of ventilator-associated pneumonia in ICU : A Retrospective cohort study

Mechanical In-Exsufflation for the prevention of ventilator-associated pneumonia in ICU : A Retrospective cohort study - Mechanical In-Exsufflation for the prevention of ventilator-associated pneumonia in ICU

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033292

Enrollment

800

Registered

2018-07-15

Start date

2018-06-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critically ill patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients was recived mechanical ventilation for at least 48 h and rehabilitation in general ICU between January 2014 and September 2017.

Exclusion criteria

Exclusion criteria: 1) Aspiration or community-acquired pneumonia, provision of mechanical ventilation for < 48 h 2) Pneumothorax and pneumomediastinum, chronic obstructive pulmonary disease with bulla 3) Severe cardiovascular failure 4) Active alveolar hemorrhage 5) The patients had sustained any injury or developed any complication 6) Patients younger than 7 years 7) Patients were received rehabilitation less than 5 days

Design outcomes

Primary

Measure	Time frame
The primary outcome of our study is incidence of VAP, defined as pneumonia developing in a person who has been on mechanical ventilation (MV) for at least 48 hours and in term of MV.	—

Secondary

Measure	Time frame
Infection-related Ventilator-Associated Complication (IVAC), the duration of MV, length of stay in ICU, mortality, the number of VAP/MV duration, Max clinical pulmonary infection score, bronchoscopy, bronchoscopy/MV duration,the event of bronchial obstruction (the event was oxyhemoglobin saturations of < 90%), the event of bronchial obstruction/duration of MV. antibiotic use day (with suspected VAP), antibiotic use day/duration of MV	—

Measure

Time frame

Infection-related Ventilator-Associated Complication (IVAC), the duration of MV, length of stay in ICU, mortality, the number of VAP/MV duration, Max clinical pulmonary infection score, bronchoscopy, bronchoscopy/MV duration,the event of bronchial obstruction (the event was oxyhemoglobin saturations of < 90%), the event of bronchial obstruction/duration of MV. antibiotic use day (with suspected VAP), antibiotic use day/duration of MV

—

Countries

Japan

Contacts

Public ContactRyota Kuroiwa

Chiba University Hospital Division of Rehabilitation Medicine

pseudoarthrosis7@chiba-u.jp043-222-7171

Outcome results