Clinical Results of Prophylactic Iodine-supported Primary TKA for Compromised Cases

Clinical Results of Prophylactic Iodine-supported Primary TKA for Compromised Cases - Prophylactic Iodine-supported Primary TKA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033222

Enrollment

Registered

2018-07-02

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Rheumatoid arthritis of knee joint

Interventions

prophylactic iodine-suported primaru TKA

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)more than grade 3 by Kellgren-Lawrence classification for OA more than grade3 by Larsen classification for RA (2)having following risk factors of PJI a history of pyogenic arthritis severe DM(HbA1c>7%) positive inflammatory markers (CRP>0.5mg/dL) due to RA etc. inactive infections in other organs bearing cancer under chemotherapy including high dose glucocorticoid(>10mg/day) hyperobesity (BMI>40)

Exclusion criteria

Exclusion criteria: a known allergy or hypersensitivity reaction against iodine based on the medical history simultaneous bilateral or revision TKA

Design outcomes

Primary

Measure	Time frame
Blood serum test Urinary iodine excretion thyroid hormone before surgery and at 1, 6 months, and 1, 3 years after surgery	—

Secondary

Measure	Time frame
postoperative roentgenogram adverse effect	—

Countries

Japan

Contacts

Public ContactTomohiro Ojima

Fukui General Hospital Dept. of Orthopaedic Surgery

ojima@ka2.so-net.ne.jp0776-59-1300

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026