Classiccal trigeminal neuralgia and neuropathic pain due to facial trauma (painful post-traumatic trigeminal neuropathy)
Conditions
Interventions
MRI examination is done once during the study period.
Sponsors
Tokyo Medical and Dntal University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Control group: Sixty males and female healthy adults aged 20 to 80. 2. Trigeminal neuralgia group:Sixty males and female patients with classical trigeminal neuralgia aged 20 to 80 years visited the Orofacia Pain Clinic at the Tokyo Medical and Dntal University, Dental Hosipital. 3. Neuropathic pain due to facial trauma(painful post-traumatic trigeminal neuropathy)group: Sixty males and female patients with neuropathic pain due to injury of the facial area aged 20 to 80 years who visited the Orofacia Pain Clinic at the Tokyo Medical and Dntal University, Dental Hosipital.
Exclusion criteria
Exclusion criteria: 1. Persons who have had some sort of pain in the maxillofacial area other than neuropathic pain due to trigeminal neuralgia or damage to the facial area by 4 weeks in advance. (In the control group, those who have had a history of some kind of pain in the maxillofacial area by 4 weeks before are excluded.) 2. Persons who have a history of neuraldia or psychiatric disorders in other parts. 3. Persons who have acute or chronic disease (multiple sclerosis, diabetes, herpes zoster etc.) causing pain. 4. Persons who are alcohol-dependent. 5. Persons wearing cardiac pacemakers. 6. Persons who have metals (arterial clips, intravascular stents, plates and bolts for repair and fixation, etc.) in the body. 7. Persons who are claustrophobic.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in brain volume and cortical thickness of grey matter obtained from MRI images are compared in typical trigeminal neuralgia group, painful post-traumatic trigeminal neuropathy group, control group of healthy subjects. | — |
Countries
Japan
Contacts
Public ContactYoko Yamazaki
Tokyo Medical and Dntal University, Dental Hosipital Orofacial Pain Clinic
Outcome results
None listed