Prospective exploratory study about prevalance of Helicobacter pylori infection for duodenal epithelial tumors

Prospective exploratory study about prevalance of Helicobacter pylori infection for duodenal epithelial tumors - PHD study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033188

Enrollment

500

Registered

2018-07-05

Start date

2018-08-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Duodenal epithelial tumors (DET) including tubular adenoma and intramucosal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: DET patient over 20 year-old planned to be performed endoscopic resection (EMR, ESD or EP) by our team

Exclusion criteria

Exclusion criteria: (1) known familiar adenomatous polyposis or hereditary non-polyposis colorectal cancer patient (2) patient with past history for upper gastrointestinal tract operation (3) patient with disorder about the function of blood coaglation, or impossibility for the adaptation according to the guideline for antithrombotic drugs of japanese gastroenterological endoscopy society (4)patient with important organ dysfunction (5)patient with another inappropreate reasons decided by the doctor

Design outcomes

Primary

Measure	Time frame
Hp infectious state about mucous characteristics expressed for every DET patients	—

Secondary

Measure	Time frame
(1) The presence of H.pylori irradication for DET patients (2) The degree of endoscopic gastritis for DET patients (3) The degree of microscopic intestinal metaplasia for DET patients (4) The pathological findings of DET (location, tumor size, macroscopic findings, color, type of histopathology, mucous characteristics of the tumor) (5) The frequency of Hp infection, the degree of endoscopic gastritis, and microscopic intestinal metaplasia at individual part of DET (oral side of papilla, papilla, and anal side of papilla) (6) The frequency of Hp infection, the degree of endoscopic gastritis, and microscopic gastritis by the mucous characteristics of DET	—

Measure

Time frame

(1) The presence of H.pylori irradication for DET patients (2) The degree of endoscopic gastritis for DET patients (3) The degree of microscopic intestinal metaplasia for DET patients (4) The pathological findings of DET (location, tumor size, macroscopic findings, color, type of histopathology, mucous characteristics of the tumor) (5) The frequency of Hp infection, the degree of endoscopic gastritis, and microscopic intestinal metaplasia at individual part of DET (oral side of papilla, papilla, and anal side of papilla) (6) The frequency of Hp infection, the degree of endoscopic gastritis, and microscopic gastritis by the mucous characteristics of DET

—

Countries

Japan

Contacts

Public ContactAtsushi Nakayama

Keio University, school of medicine Cancer center, division of research and development for minimal invasive treatment

anakayama34@keio.jp0333531211

Outcome results