Comparison of visual outcomes between bilateral implantation of a trifocal intraocular lens (IOL) and combined implantation of a bifocal IOL with different near addition power: a prospective nonrandomized study

Comparison of visual outcomes between bilateral implantation of a trifocal intraocular lens (IOL) and combined implantation of a bifocal IOL with different near addition power: a prospective nonrandomized study - Bilateral trifocal IOLs versus combined bifocal IOLs

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033175

Enrollment

Registered

2018-06-28

Start date

2014-01-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Interventions

A trifocal IOL group (n=32) implanted bilaterally with a new trifocal IOL (Alcon PanOptix

TFNT00). A combined bifocal group (n=46) implanted with a bifocal IOL with +3.0D near addition power (SN60D1) in the dominant eye and +4.0D near addition power (SN60D3) in the nondominant eye.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients who elected to undergo bilateral phacoemulsification and implantation of multifocal IOLs

Exclusion criteria

Exclusion criteria: Preoperative exclusion criteria were patients with any pathology of the cornea, macula or optic nerve; opaque media other than cataract; history of ocular inflammation or surgery; corneal astigmatism of 1.0 D or more; marked irregular corneal astigmatism; amblyopia; patients who had participated in another clinical trial; and any difficulties with examinations, analyses, or follow-up. Intraoperative exclusion criteria were a small pupillary diameter that required pupil expansion procedures and eventful surgery.

Design outcomes

Primary

Measure	Time frame
1) Binocular uncorrected and corrected visual acuity (VA) at various distances measured using the all-distance vision tester (KOWA AS-15), 2) Contrast visual acuity (CAT-2000) with and without glare, 3) Near stereoacuity (Titmus stereo test), 4) Number (%) of patients who reported glare and halo symptoms 5) Wavefront higher-order aberrations (HOAs); total, coma-like, and spherical-like HOAs 6) Pupil diameter, corneal astigmatism, manifest spherical equivalent value	—

Measure

Time frame

1) Binocular uncorrected and corrected visual acuity (VA) at various distances measured using the all-distance vision tester (KOWA AS-15), 2) Contrast visual acuity (CAT-2000) with and without glare, 3) Near stereoacuity (Titmus stereo test), 4) Number (%) of patients who reported glare and halo symptoms 5) Wavefront higher-order aberrations (HOAs); total, coma-like, and spherical-like HOAs 6) Pupil diameter, corneal astigmatism, manifest spherical equivalent value

—

Countries

Japan

Contacts

Public ContactKen Hayashi

Hayashi Eye Hospital Department of Ophthalmology

hayashi-ken@hayashi.or.jp092-431-1680

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026