Confirmation of appropriate peripheral venous catheter placement by microbubble detection after normal saline administration using ultrasonography in pediatric patients: a randomized controlled trial

Confirmation of appropriate peripheral venous catheter placement by microbubble detection after normal saline administration using ultrasonography in pediatric patients: a randomized controlled trial - Confirmation of appropriate peripheral venous catheter placement by microbubble detection after normal saline administration using ultrasonography in pediatric patients: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033134

Enrollment

300

Registered

2018-06-25

Start date

2018-06-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

In ultrasound group, we perform microbubble test (MBT) as follows. We visualize patients&#39

right atrium by cardiac ultrasonography (subcostal or apical four chamber view) and inject normal saline thorough peripherally venous catheters, which are already or newly inserted. We investigate whe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Pediatric patients whose body weights are under 15kg, admit to PICU of Osaka Women's and Children's hospital, and peripheral venous catheter were newly or already inserted.

Exclusion criteria

Exclusion criteria: Patients whose parents do not agree with this study. Vasoactive agents are continuously administered through the peripheral venous catheter. Appropriate four chamber view cannot be obtained. Volume injection is restricted. Hemodynamic status is unstable. Patients who underwent Glenn operation or Fontan operation. Anatomical abnormality of Vena cava.

Design outcomes

Primary

Measure	Time frame
The rate which both tests are positive in case peripheral venous catheter was appropriately positioned intravenous.	—

Secondary

Measure	Time frame
The rate which both tests are negative in case peripheral venous catheter was positioned extravenous.	—

Countries

Japan

Contacts

Public ContactJun Takeshita

Osaka Women's and Children's Hospital Department of Intensive Care Medicine

t-k-s-t@koto.kpu-m.ac.jp0725-56-1220

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026