Prevention of colonization of S. aureus
Conditions
Interventions
Administration of three bacterial species of Bifidobacterium
Administration of one bacterial spece of Bifidobacterium.
Sponsors
Chiba University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Less than 2,000g of low birth weight infants who were admitted to NICU and GCU.
Exclusion criteria
Exclusion criteria: 1) Neonate whose birth weight is 2000g or more. 2) Infants with a surgical disease (esophageal atresia, diaphragmatic hernia, etc.), long-term enteral nutrition / oral medication administration can not be expected. 3) Neonate who judged to be ineligible by research facility director or research doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Colonization rate of S. aureus in specimens collected in feces, pharynx (nasal culture) up to 4 weeks after birth in each group. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of the numbers of three strains Bifidobacterium and Staphylococcus aureus in each group in feces collected at 1 week, 2 weeks and 4 weeks after birth. Difference between the age of each group and birth weight reversion Correlation between weight gain rate and each group at week 40 weeks in preterm infants | — |
Countries
Japan
Contacts
Public ContactKenichi Takeshita
Teikyo University Chiba medical center Department of Pediatrics
Outcome results
None listed