Healthy adults
Conditions
Interventions
Ingestion of test supplement for 4 consecutive weeks
Ingestion of placebo for 4 consecutive weeks
Sponsors
TTC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Subjects aged from 45 to 65 years old (2) Subjects with eye strain by VDT load
Exclusion criteria
Exclusion criteria: (1)Subjects who have amblyopia or strabismus (2) Subjects who have history of the organic eye disease (e.g., cataract, glaucoma, diabetic retinopathy, and age-related macular degeneration) (3)Subjects who are under medication and/or medical treatment for eye disease (e.g., asthenopia and dry eye) (4)Subjects who have history of the autoimmune disease (e.g., Sjogren syndrome, Basedow's disease, Hashimoto's disease, rheumatoid arthritis) (5)Subjects who have a severe ametropia from result of screening test (6)Subjects who use eye drops (including over-the-counter medicine) more than 4 days in a week (excluding artificial tears type eye drop (e.g., Soft santear, artificial tear Mytear eye drop) (7)Subjects who routinely take food with health claim or health foods, quasi-drug, or medicine related to eye wellness / or take them a month before start of this study (8)Subjects who have history or plan in study period to take punctual plug and punctual closing surgery (9)Subjects who have history of ophthalmic surgery (including LASIK) within a year before start of study or have a schedule of ophthalmic surgery in study period (10)Subjects who have suffering from any disease or who with a case history of a serious disease that needed medication (11)Subjects who have possibilities for emerging allergy related to the study (12)Subjects who can't carry out the VDT loading test during study period (13)Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (14)Subjects who have under treatment or a history of serious disease (15)Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on baseline examination (16)Subjects who intend to become pregnant or lactating (17)Subjects who have participated in other clinical study (18)Subjects who are judged as unsuitable by doctor for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The scores of questionnaire on eye strain, in variation of before and after of VDT load | — |
Secondary
| Measure | Time frame |
|---|---|
| The scores of questionnaire on eye strain before VDT load, The scores of questionnaire on eye strain after VDT load, DEQS, Tear breakup time, Corneal Fluorescein Staining Pattern, Schirmer's test 1 Subgroup analysis using scores of questionnaire and other measurements | — |
Countries
Japan
Contacts
Public ContactHiroyasu Shimada
TTC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed