Assessment of preload reserve in patients with heart failure with preserved ejection fraction using leg positive pressure maneuver

Assessment of preload reserve in patients with heart failure with preserved ejection fraction using leg positive pressure maneuver - Assessment of preload reserve for patients with heart failure with preserved ejection fraction

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000033091

Enrollment

Registered

2018-06-30

Start date

2018-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic heart failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)control subjects are defined as who don't have any heart disease (2)heart failure patients are defined as who are admitted with hospital due to heart failure (3)age between 20 to 90 (4)gender is unmentioned (5)patients who agree to participate in this trial (6)hemodynamically stable patients under standard heart failure therapy (7)ejection fraction >50%

Exclusion criteria

Exclusion criteria: (1)hypotension (BP<90/50mmHg) or severe hypertension (BP>160/90mmHg) (2)acute organ damage other than heart within 3 months (3)patients with NYHA functional class IV (4)patients with severe renal or liver disease (5)pregnant woman (6)the patients with, or the history of deep venous thrombosis (7)those who have active trauma at the lower limbs (8)valvular heart disease more than moderate (9)atrial fibrillation

Design outcomes

Primary

Measure	Time frame
change in forward stroke volume and ventricular filling pressure during leg positive pressure maneuver	—

Countries

Japan

Contacts

Public ContactKensuke Matsumoto

Kobe University Graduate School of Medicine Department of Internal Medicine Division of Cardiovascular Medicine

kenmatsu@med.kobe-u.ac.jp078-382-5846

Outcome results