Skip to content

Exploring possible sources of bias in diagnostic test accuracy beyond the QUADAS (Quality Assessment of Diagnostic Accuracy Studies): a study protocol for a meta-epidemiological study

Exploring possible sources of bias in diagnostic test accuracy beyond the QUADAS (Quality Assessment of Diagnostic Accuracy Studies): a study protocol for a meta-epidemiological study - Exploring possible sources of bias in diagnostic test accuracy:study protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000033079
Enrollment
70
Registered
2018-06-22
Start date
2018-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systematic reviews

Interventions

None listed

Sponsors

Kobe University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: We will include systematic reviews (SRs) in which the authors evaluate the DTA of one or more tests against a reference standard. We will only include DTA reviews with meta-analyses that include 10 or more primary studies and provide data to reconstruct 2*2 tables.

Exclusion criteria

Exclusion criteria: We will exclude narrative reviews, genomic reviews, animal reviews, reviews that apply a language or quality restriction, reviews that assess the analytical validity of tests, and reviews that only evaluate other measures of diagnostic performance such as reproducibility and reliability.

Design outcomes

Primary

MeasureTime frame
Study characteristics to be estimated will include publication year (before 2003 or after 2004), impact factor of publication journal, country (high or middle/low income), type of language (English or not), sample size, healthcare setting (primary healthcare or not), funding source (industrial sponsorship or not), publication status (full-publication or not), and number of study centers (single center or multicenter).

Countries

Japan

Contacts

Public ContactAkira Onishi

Kobe University Graduate School of Medicine Department of Rheumatology and Clinical Immunology

aonishi@med.kobe-u.ac.jp81-78-382-6207

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026