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Effects of low dose droperidol on transcranial electrical motor-evoked potentials.

Effects of low dose droperidol on transcranial electrical motor-evoked potentials. - Effects of low dose droperidol on transcranial electrical motor-evoked potentials.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000033068
Enrollment
20
Registered
2018-07-01
Start date
2018-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic scoliosis

Interventions

First we measure the control amplitude of the MEP. Next, 20 microgram per kilogram of DROLEPTAN INJECTION is administered. Measure MEP every 2 minutes for 10 minutes. After 10 minutes, measure SSEP, M

Sponsors

Niigata University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: The subjects were female patients aged 12 to 20 who were scheduled to perform corrective surgery for idiopathic scoliosis, which requires the intraoperative MEP measurement of ASA 1-2.

Exclusion criteria

Exclusion criteria: Those with the following disorders in the past history; convulsive seizures, epilepsy, intracranial diseases, neuromuscular diseases, extrapyramidal diseases, peripheral nerve diseases, severe cardiovascular lesions, prolonged QT syndrome, hepatic dysfunction, renal dysfunction , Mental illness and mental retardation Beta blockade or MAO inhibitor is administered. What can not understand the purpose of this research. Those with hypersensitivity to the components of the drug to be used. Those weighing less than 30 kg. Other, exclude those who judge it as inappropriate for this research.

Design outcomes

Primary

MeasureTime frame
The amplitude of the motor-evoked potentials obtained from the left tibialis anterior muscle in the low dose droperidol administration group and saline administration group.

Secondary

MeasureTime frame
MEP amplitude from other muscles, latency of SSEP and MEP, amplitude of evoked electromyography (M wave, H wave, F wave).

Countries

Japan

Contacts

Public ContactYusuke Mitsuma

Niigata University Medical & Dental Hospital Division of Anesthesiology

y.mikan.mikan.mikan@gmail.com070-5562-4404

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026