Healthy adult volunteers with a fasting blood glucose level in the normal range or the boundary range (less than 126 mg/dL).
Conditions
Interventions
None listed
Sponsors
Association for Salacia Promotion
Review team Mr. Kenji Ikeda, Fujifilm Corporation Dr. Yuriko Oda, Fujifilm Corporation Dr.. Eriko Kishino, Ensuikou Sugar Refining Co. Ltd. Research Collaborator Professor Horoharu Kamioka, Tokyo University of Agriculuture Dr. Takahiro Yoshizaki, Toyo University Ms. Mari Makishi, Toho University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Systematic literature search using scientific databases and registered databases for clinical trials and systematic review will be performed. Key inclusion criteria as follows: Participants: Healthy adult volunteers with a fasting blood glucose level in the normal range or the boundary range (less than 126 mg/dL). Intervention: Intake the foods containing salacia-derived salacinol more than 0.02 mg/meal. Comparison: Intake the foods not containing salacia-derived salacinol. Outcome: The suppression effects of postprandial hyperglycemia (see above outcome column) Study design: Adopt randomized, quasi-randomized and non-randomized (parallel group or cross over) comparison test.
Exclusion criteria
Exclusion criteria: The literature which does not meet the key inclusion criteria will be excluded. Intervention tests without a placebo intake group are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the suppression effect on the postprandial hyperglycemia (ref1). Specifically, it is taken as the blood glucose level after ingestion of carbohydrate or a meal containing carbohydrate. (ref1) Since the fluctuation of blood glucose level after meals varies depending on the types or contents of carbohydrates loaded, such as a drink containing sucrose or a steamed rice, the primary outcome will be evaluated comprehensively using the Cmax and/or the area under the curve (AUC) of postprandial blood glucose level. | — |
Countries
Japan
Contacts
Public ContactYoshiki Sakaino
Association for Salacia Promotion Office
Outcome results
None listed