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Analysis of tap test responsiveness in neurodegenerative disorders

Analysis of tap test responsiveness in neurodegenerative disorders - Analysis of tap test responsiveness in neurodegenerative disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000033026
Enrollment
84
Registered
2018-07-01
Start date
2018-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson&#39

Interventions

Cerebrospinal fluid tap test+sham tap test Cerebrospinal fluid tap test+sham tap test Cerebrospinal fluid tap test+sham tap test

Sponsors

Tokyo Medical and Dental University, Department of Neurology and Neurological Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with a clinical diagnosis of iNPH, PSP, PD/DLB were enrolled.

Exclusion criteria

Exclusion criteria: 1. patients with intracranial hypertension 2. patients who have infection at puncture site 3. patients with patients with hemorrhagic diathesis 4. patients who have antiplatelet drug or anticoagulant drug and are difficult to stop such a medication 5. patients with metallic implants 6. patients with claustrophobia 7. patients with unstable vital signs 8. patients who are under 40 years old or who can not express their intension 9. pregnant women 10. patients who are considered to be not suitable for the study

Design outcomes

Primary

MeasureTime frame
Gait velocity variability before and after tap test

Secondary

MeasureTime frame
Stride length and height of the legs variability before and after tap test Cognitive function test variability before and after tap test OABSS and IPSS before and after tap test Functional connectivity variability on functional MRI study before and after tap test

Countries

Japan

Contacts

Public ContactTakaaki Hattori

Tokyo Medical and Dental University Department of Neurology and Neurological Science

takaaki-hattori@umin.ac.jp03-3813-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026