Study of efficacy and safety of dose reduction in the oral cavity by target volume definition using PET/CT for intensity-modulated radiation therapy of head and neck cancers

Study of efficacy and safety of dose reduction in the oral cavity by target volume definition using PET/CT for intensity-modulated radiation therapy of head and neck cancers - Study of efficacy and safety of dose reduction in the oral cavity by target volume definition using PET/CT for intensity-modulated radiation therapy of head and neck cancers

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000033007

Enrollment

Registered

2018-06-16

Start date

2018-06-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head-and-neck cancer

Interventions

Patients whose target volume is defined by PET/CT and in whom radiation therapy is performed according to the defined planning target volume

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with head neck cancer who meet all of the following criteria; 1.Age over 20 2.Pathologically confirmed head neck cancer 3.The neck (at the oral cavity level) will be irradiated with a dose of 50Gy or higher 4.Performance status (ECOG) 0-2 5.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Patients have psychiatric disorders that may comprise the patient's ability to receive radiotherapy 2.Patients who is considered ineligible for enrolling the study by a principal investigator or sub-investigator

Design outcomes

Primary

Measure	Time frame
The target volume (at the oral cavity level) defined by PET/CT and the radiation dose in the oral cavity	—

Secondary

Measure	Time frame
Acute and late adverse events during and after the radiation therapy The presence or absence of local recurrence and distant metastasis during the 3-year post-treatment period, and overall survival	—

Countries

Japan

Contacts

Public ContactKosugi Yasuo

Juntendo University Department of Radiation Oncology

ykosugi@juntendo.ac.jp+81338133111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026