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Mechanisms of Embolic Stroke Clarified by Transesophageal Echocardiography for Embolic Stroke of Undetermined Source/Cryptogenic Stroke

Mechanisms of Embolic Stroke Clarified by Transesophageal Echocardiography for Embolic Stroke of Undetermined Source/Cryptogenic Stroke - CHALLENGE ESUS/CS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000032957
Enrollment
700
Registered
2018-06-12
Start date
2017-05-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cryptogenic stroke/Embolic stroke of undetermined source

Interventions

None listed

Sponsors

Juntendo University Faculty of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Acute ischemic stroke within 7 days of onset 2. Cryptogenic stroke/Embolic stroke of undetermined source a. Non-lacunar stroke demonstrated on CT or MRI b. Absence of the extracranial or intracranial atherosclerosis causing >50% luminal stenosis in the corresponded arteries c. Absence of major cardiac embolic diseases d. Lack of other determined stroke etiologies

Exclusion criteria

Exclusion criteria: Patients considered as inappropriate by investigators

Design outcomes

Primary

MeasureTime frame
Prognosis

Countries

Japan

Contacts

Public ContactYuji Ueno

Juntendo University Faculty of Medicine Neurology

yuji-u@juntendo.ac.jo03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026