ST-elevation acute myocardial infarction (STEMI)
Conditions
Interventions
Excimer laser catheter
Standard treatment
Sponsors
Tokai University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients to whom PCI treatment for Anterior STEMI is indicated [Main selection criteria] First-episode Anterior STEMI patients within 6 hours of onset that satisfy electrocardiogram criteria Patients who are 21 years of age or older at the time of consent acquisition Patient who the patient himself agreed in writing
Exclusion criteria
Exclusion criteria: Patients presenting cardiac shock at the time of visit Patients whose target lesions are left main trunk, circumflex, right coronary artery, distal anterior descending branch Patients who have TIMI 2, 3 at the initial imaging Patients with a reference vessel diameter of 2.5 mm or less Patients determined to lack consent ability for mental or other reasons Patient who is judged inappropriate by research researcher or research sharing doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| myocardial salvage = (Risk at area measured by BMIPP 3-9 days after p-PCI) - (Infarct size measured by Tc99m-tetrofosmin at 6 months after p-PCI) myocardial salvage index (%) = myocardial salvage / Risk at area measured by BMIPP 3-9 days after p-PCI x 100 | — |
Secondary
| Measure | Time frame |
|---|---|
| Myocardial salvage, infarct size, microvascular obstruction by MRI Left ventricular ejection fraction by TF scintigraphy at 6 months 12 months, 36 months, 60 months Clinical end point Intra-stent tissue volume by OCT | — |
Countries
Japan
Contacts
Public ContactFumie Saito
Tokai University Department of Cardiovascular Medicine
Outcome results
None listed