Idiopathic interstitial pneumonias (IIPs)
Conditions
Interventions
None listed
Sponsors
Tokai University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Pre-existing idiopathic interstitial pneumonia is proved or suspected 2. Acute worsening or development of dyspnea within 1 month 3. Requirement for oxygen therapy to maintain SpO2 >90%, or increase in oxygen flow to maintain SpO2 >90% in cases under long-term oxygen therapy 4. New ground-glass opacity in the lungs on chest computed tomography 5. Written informed consent has been obtained
Exclusion criteria
Exclusion criteria: 1. Connective tissue disease-related interstitial lung disease (CTD-ILD) 2. Hypersensitivity pneumonia 3. Cryptogenic organizing pneumonia 4. Radiation-induced lung injury 5. Pulmonary lymphangitic carcinomatosis 6. Patients who cannot perform the tests conducted in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Proportion and clinical characteristics of IIP cases with acute respiratory failure caused by a factor(s) other than acute exacerbation 2. Clinical characteristics, treatment responses, and prognosis of the patients with acute exacerbation according to a new classification of the severity 3. Clinical characteristics and prognosis of responders and non-responders to glucocorticoid treatment of acute exacerbation 4. Long-term QOL, respiratory function, prevalence of re-exacerbation, and prognosis observation of acute exacerbation survivors 5. Prevalence of acute exacerbation due to specific triggers (drug, surgery, infection, etc.) and their treatment response and prognosis 6. Factors associated with prognosis of acute exacerbation | — |
Countries
Japan
Contacts
Public ContactTakahisa Takihara
Tokai University School of Medicine Division of Pulmonary Medicine, Department of Medicine
Outcome results
None listed