healthy elderly people
Conditions
Interventions
Odor stimulation by aromas (two hours exposure to odor stimulation twice a day in the morning and evening over three months)
Odor stimulation by ethanol (two hours exposure to odor stimulation twice a
Sponsors
Keio University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Ability to both understand and agree with informed consent in Japanese Ability to perform the all tests required on the designated day after the agreement with informed consent A score of 24 or more on the MMSE Olfactory ability demonstrated as normal by the test of T&T olfactometer
Exclusion criteria
Exclusion criteria: Any substance addiction (except nicotine addiction) in the current or past history Education history of 6 years or less Any substance addiction (except nicotine addiction) in the current or past history Currently receiving any psychotropic medication such as antidepressant, antipsychotics or tranquilizers including sleeping pills Medical history of psychiatric or neurological diseases, including schizophrenia, depressive disorders or anxiety disorders, potentially influencing the olfactory ability (ruled out by the M.I.N.I.(Mini-International Neuropsychiatric Interview) Severe physical disease including liver, renal or endocrine disability Any disease potentially causing the olfactory disability Routinely receiving aromatherapy treatments Routinely using softener, fragrance or perfume with strong smell
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PASAT(Paced Auditory Serial Addition Test) | — |
Secondary
| Measure | Time frame |
|---|---|
| MMSE, PHQ-9, GAD-7, SDISS,Well-being(the relevant four items from CES-D), RAVLT, Symbol Digit Modalities Test, Pittsburgh Sleep Quality Index, T&T Olfactometer | — |
Countries
Japan
Contacts
Public ContactMika Konishi
Keio University School of Medicine Department of Neuropsychiatry
Outcome results
None listed