Association of the Serum Triglyceride/high-density Lipoprotein Cholesterol Ratio with Low-density Lipoprotein Heterogeneity: A Pilot Cross-sectional and Longitudinal Study

Association of the Serum Triglyceride/high-density Lipoprotein Cholesterol Ratio with Low-density Lipoprotein Heterogeneity: A Pilot Cross-sectional and Longitudinal Study - TG/HDL ratio and LDL heterogeneity

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000032934

Enrollment

700

Registered

2018-06-11

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with one additional risk factor for atherosclerosis.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The criterion for patient registration in the cross sectional study was the presence of one or more risk factors for atherosclerosis.

Exclusion criteria

Exclusion criteria: Patients were not enrolled if they met any of the following exclusion criteria: presence of hepatic dysfunction (serum alanine aminotransferase and aspartate aminotransferase levels 2 times the upper limit of normal),known malignant disease, diagnosis of acute coronary syndrome within 3 months prior to the study, and/or serum TG 400 mg/dL.

Design outcomes

Primary

Measure	Time frame
1)the relationships between the serum TG/HDL-C ratio and LDL-heterogeneity, as assessed by polyacrylamide-gel electrophoresis (PAGE)in patients with one or more risk factors for ACVD. 2)Furthermore, we examined the relationship between the changes in the TG/HDL-C ratio and the change in the LDL particle size in cases in which additional measurements could also be conducted 1 year later.	—

Countries

Japan

Contacts

Public ContactShigemasa Tani

Nihon University Hospital Health Planning Center

tanishigem@yahoo.co.jp03-3293-1711

Outcome results