Observational study on gene mutation and prognosis for patients with resectable pancreatic cancer

Observational study on gene mutation and prognosis for patients with resectable pancreatic cancer - Observational study on gene mutation and prognosis for patients with resectable pancreatic cancer

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000032917

Enrollment

219

Registered

2018-07-01

Start date

2018-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient who can obtain medical treatment content from medical record Patients who underwent surgical treatment for pancreatic cancer at Kobe university hospital between January 2008 and May 2017

Exclusion criteria

Exclusion criteria: Patients who did not participate in this research from published information Patients under 20 years of age

Design outcomes

Primary

Measure	Time frame
The relationship between gene mutation (KRAS, TP53, CDKN2A, SMAD4) and prognosis in patients with surgically treated pancreatic cancer	—

Secondary

Measure	Time frame
The relationship between the following items and the relation between gene mutation or prognosis in pancreatic cancer patients who underwent surgical treatment 1)presence or absence of IPMN coexistence 2)desmoplastic change 3)diabetic status 4)smoking history 5)local immune responses(TIL:Tumor Infiltrating Lymphocyte, TLS:Tertiary Lymphoid Structure ) 6)systemic immune responses(ALC:Absolute Lymphocyte Counts, ANC:Absolute Neutrophil Counts, NLR:Neutrophil-to-Lymphocyte Ratio) The relationship between desmoplastic change and preoperative image findings	—

Measure

Time frame

The relationship between the following items and the relation between gene mutation or prognosis in pancreatic cancer patients who underwent surgical treatment 1)presence or absence of IPMN coexistence 2)desmoplastic change 3)diabetic status 4)smoking history 5)local immune responses(TIL:Tumor Infiltrating Lymphocyte, TLS:Tertiary Lymphoid Structure ) 6)systemic immune responses(ALC:Absolute Lymphocyte Counts, ANC:Absolute Neutrophil Counts, NLR:Neutrophil-to-Lymphocyte Ratio) The relationship between desmoplastic change and preoperative image findings

—

Countries

Japan

Contacts

Public ContactAtsuhiro Masuda

Kobe University Graduate School of Medicine Gastroenterology

atmasuda@med.kobe-u.ac.jp078-382-6305

Outcome results