Adult
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Desk workers who can visit around Tokyo Station by themselves. 2) Workers and resignees at Kanagawa prefecture. People in Kanagawa. 3) People older than 30 years and younger than 79 years. 4) Desk workers.
Exclusion criteria
Exclusion criteria: 1) People who cannot attend the second MRI examination one year later. 2) People who cannot obtain informed consent due to cognitive impairment. 3) People who cannot undergo MRI examination due to claustrophobia. 4) People who cannot undergo MRI examination due to metal in the body. 5) People with a history of surgery in either knee. 6) People who visited hospital for injury in either knee for more three months. 7) People who have osteoarthritis or history of fracture in either lower extremity. 8) People who are diagnosed as collagen disease such as rheumatoid arthritis. 9) People who have any knee injection or arthrocentesis. 10) People who are poor general condition. 11) People who are pregnant or possible pregnant. 12) People who have a consciousness of doing vigorous sports such as full marathon, triathlon, weight lifting. 13) People for whom involved doctors decide as not appropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3D MRI projected cartilage area ratio by generations and transition of projected cartilage area ratio for one year. | — |
Countries
Japan
Contacts
Tokyo Medical and Dental University Center for Stem cell and Regenerative Medicine