Healthy adult
Conditions
Interventions
Oral glucose tolerance test after intake of high cacao chocolate
Only oral glucose tolerance test
Sponsors
The University of Shizuoka
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects who competent to consent and give voluntary consent in writing with full understanding after receiving explanation of this study aim and contents.
Exclusion criteria
Exclusion criteria: 1) Subjects who are under treatment for chronic disorders 2) Subjects whose HbA1c level is greater than 6.5% at the second screening 3) Subjects whose blood glucose level is greater than 126 mg/dl when fasting at the second screening 4) Subjects who are allergic to chocolate, milk, soybeans, wheat, beef, chicken, pork, salmon, crab, banana, apples, and oranges 5) Subjects with headache induced by intake of chocolates 6) Subjects who highly intake cacao products on a daily basis (high cacao chocolate: 70 g or more/ week, milk chocolate :140 g or more/ week) 7) Subjects taking medicines (such as hypoglycemic drugs) with function claims that potentially influence the outcome of this study on a daily basis, or those who intend to take these during this study 8) Subjects whose sexual cycle is unstable (persons with sex cycle other than 28 days) 9) Subjects who have participated in other clinical and monitoring studies within 1 month before screening or who plan to participate in other clinical trials after this clinical trial consent 10) Subjects who are pregnant, or plan to get pregnant during the study period 11) Subjects who are breast-feeding 12) Alcohol-heavy drinkers (drinkers with an average daily of over 60 g in terms of pure alcohol) 13) Subjects who are judged as ineligible by the examination director and doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma glucose levels | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum insulin levels, non-esterified free fatty acid concentration, glucagon concentration, GLP-1 concentration | — |
Countries
Japan
Contacts
Public ContactHidekazu Arai
The University of Shizuoka Laboratory of Clinical Nutrition and Management, School of Food and Nutritional Sciences
Outcome results
None listed