periodontal disease
Conditions
Interventions
Isolation of subcutaneous fat
Sponsors
Tohoku University Graduate School of Dentistry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Disease name: Tohoku University hospital 5F Foundation for dental outpatients diagnosed as periodontal disease and able to agree with the research plan (2) stage, stage: mild periodontal disease with gingivitis (3) Performance Status Grade 0 or 1: (Health condition that normal wound healing and fat collection can be expected) (4) Age 30 years old and over, under 50 years (at registration) (5) Gender does not matter
Exclusion criteria
Exclusion criteria: (Exclusion to affect effectiveness evaluation) (1) Study subjects who have complicated diabetes, autoimmune disease, cardiovascular disease, etc. and can not expect wound healing (2) Research subjects who are too thin to take out fat (Exclusion for affecting safety evaluation) (3) Research subjects who have allergy to metals (4) Local anesthesia (xylocaine) Research subjects with allergies (5) Women who are pregnant, have the possibility of pregnancy, are within 28 days of birth, are lactating
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Isolation of adipose derived stem cells in cell processing center of Tohoku university hospital and safety test (infection test), purity test(FACS analysis) | — |
Secondary
| Measure | Time frame |
|---|---|
| Differentiation ability of adipose derived stem cells into osteoblast. | — |
Countries
Japan
Contacts
Public ContactKeisuke Handa
Tohoku University Graduate School of Dentistry Department of Restorative Dentistry Division of Operative Dentistry
Outcome results
None listed