Efficacy of combined Proton-pump inhibitor and Acotiamide treatment for non-erosive reflux disease

Efficacy of combined Proton-pump inhibitor and Acotiamide treatment for non-erosive reflux disease - Efficacy of combined PPI and Acotiamide treatment for NERD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032699

Enrollment

Registered

2018-06-01

Start date

2018-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-erosive reflux disease

Interventions

Proton-pump inhibitor Proton-pump inhibitor, Acotiamide

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: NERD (non-erosive reflux disease) patients

Exclusion criteria

Exclusion criteria: 1) Patients contraindicated for study treatment 2) Patients under 20 years old 3) Patients unsuited for this study at a physician's discretion

Design outcomes

Primary

Measure	Time frame
Improvement rate of symptom score (modified F scale and Izumo scale) 4 weeks after treatment.	—

Secondary

Measure	Time frame
The incidence of adverse events.	—

Countries

Japan

Contacts

Public ContactTakahito Toba

Toho University Omori Medical Center Gastroenterology

takahito.toba@med.toho-u.ac.jp03-3762-4151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026