Treatment of chronic wounds is a big clinically challenging based on low graft take rates associated with current surgery, and the cell utilization and therapeutic effects for chronic wounds need to be improved.
Conditions
Interventions
patients received FN coating wound bed combined with autologous skin cell suspension and Split-thickness skin grafting (experimental group)
patients received autologous skin cell suspension and Split-
Sponsors
The First Affiliated Hospital of Sun Yat-sen University Department of Burn Surgery
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with a chronic wound (defined as a wound that remained unhealed for more than 4 weeks) which required surgical debridement and skin grafting were eligible.
Exclusion criteria
Exclusion criteria: 1.Pregnant women and people aged less than 18 years old; 2.Pre-existing medical conditions that could potentially interfere with wound healing; 3.Patients diagnosed with other medical conditions that could hinder wound healing. 4.Patients considered to be at an aesthetic risk and refusal to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of complete wound healing at 28 days (full re-epithelialization, without any requirement for dressing) | — |
Secondary
| Measure | Time frame |
|---|---|
| The time to achieve complete wound closure and treatment-related complications, included pain and itching | — |
Countries
Asia(except Japan)
Contacts
Public ContactPeng Wang
The First Affiliated Hospital of Sun Yat-sen University Department of Burn Surgery
Outcome results
None listed