Effects of polyphenol-enriched extracts from Wakame on muscle atrophy caused by cachexia

Effects of polyphenol-enriched extracts from Wakame on muscle atrophy caused by cachexia - Effects of polyphenol-enriched Wakame diets on muscle atrophy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032592

Enrollment

Registered

2018-07-01

Start date

2021-01-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cachexia

Interventions

Wakame Extracts with Chinese soup, 1.5 g/day, 28 days

flour for control group, 1.5 g/day, 28 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Pre-cachectic condition: In a state deviating from a normal state, weight loss is within 5%, a condition accompanied by anorexia and metabolic abnormality

Exclusion criteria

Exclusion criteria: Poor oral ingestion, accompanied by systemic inflammation, the condition of cachexia progressed (weight loss is 5% or more; or BMI 20% or less and weight loss 2% or more; or sarcopenia (muscle mass decreased, muscular strength and body function is decreased, BMI less than 18.5) and weight loss is 2% or more)

Design outcomes

Primary

Measure	Time frame
muscle volume	—

Secondary

Measure	Time frame
food intake, body weight, tumor size	—

Countries

Japan

Contacts

Public ContactTakeshi Nikawa

Tokushima University Graduate School Institute of Medical Biosciences, Department of Nutritional Physiology

nikawa@tokushima-u.ac.jp088-633-9248

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026