Breast cancer
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: elective surgery of breast cancer
Exclusion criteria
Exclusion criteria: 1)under 20 years old 2)Hard to communication 3)Unable to establish the informed consent 4)Hepatic dysfunction 5)Renal dysfunction 6)serum albumin under 3.0g/dl 7)Allergy to amid type local anesthetic 8)Medication of antiarrysmitic drug 9)Medication of anticoagulants/anti-plateletdrug 10)Coagulopathy PT-INR >1.5 11)Any other confition whitch treated as contraindication of peripheral nerve blck
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma ropivacaine concentration The timings of sampling are 2.5,5,10,15,30,45,60,90,120min after peripheral nerve block. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical symptom of local anesthetic toxicity | — |
Countries
Japan
Contacts
Teikyo university shcool of medicine hospital Anesthesisa