Effects of Dietary Intake of Broccoli Sprouts on Intestinal Microbiota and Defecation in Human Subjects -2nd Trial-

Effects of Dietary Intake of Broccoli Sprouts on Intestinal Microbiota and Defecation in Human Subjects -2nd Trial- - Effects of Broccli Sprouts on Human Intestinal Microbiota and Defecation -2nd Trial-

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032565

Enrollment

Registered

2018-05-13

Start date

2018-03-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic functional constipation

Interventions

broccoli sprouts (20 g/day = sulforaphane 88 mg/day for 4 weeks) alfalfa sprouts (20 g/day = sulforaphane 0 mg/day for 4 weeks)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: female human subjects, who are basically healthy other than having chronic constipation, whose constipation score is greater than 2 points

Exclusion criteria

Exclusion criteria: 1. Subjects who have organic diseases in gastrointestinal tracts. 2. Subjects who are regularily using drugs, which influence on defecation. 3. Subjects who are regularily taking foods, which influence on defecation

Design outcomes

Primary

Measure	Time frame
composition of beneficial and pathogenic intestinal micribiota in stool sampleobtained at 4 weeks after intervention	—

Secondary

Measure	Time frame
constipation score	—

Countries

Japan

Contacts

Public ContactAkinori Yanaka

University of Tsukuba Faculty of Medicine, Hitachi Medical Education and Research Center

ynk-aki@md.tsukuba.ac.jp0294-23-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026