post-polio syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Prior paralytic poliomyelitis with evidence of motor neuron loss, as confirmed by history of the acute paralytic illness, signs of residual weakness and atrophy of muscles on neurological examination. 2. A period of partial or complete functional recovery after acute poliomyelitis, followed by an interval (usually 15 years or more) of stable neurological function. 3. Gradual or sudden onset of progressive and persistent new muscle weakness or abnormal fatigability (decreased endurance), with or without generalized fatigue, muscle atrophy, or muscle and joint pain (Sudden onset may follow a period of inactivity, or trauma or surgery). Less commonly, symptoms attribute to post-polio syndrome include new problems with breathing or swallowing. 4. Symptoms persist for at least a year. 5. Exclusion of other neurological, medical, and orthopaedic problems as cause of symptoms.
Exclusion criteria
Exclusion criteria: History of epilepsy, use of anticonvulsant, implantation of metal device intracranially
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the difference in the Multidimensional Fatigue Inventory after intervention | — |
Countries
Japan
Contacts
University of occupational and environmental health Department of rehabilitation medicine