Virtual bronchoscopic navigation as an aid to CT-guided transbronchial biopsy improves the diagnostic yield for small peripheral pulmonary lesions

Virtual bronchoscopic navigation as an aid to CT-guided transbronchial biopsy improves the diagnostic yield for small peripheral pulmonary lesions - Diagnostic yield with VBN and CT-TBB

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032484

Enrollment

100

Registered

2018-05-08

Start date

2011-11-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer (including suspect of lung cancer)

Interventions

Conventional CT-guided transbronchial biopsy with or without virtual bronchoscopic navigation (VBN) Using VBN is during procedure only.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with small PPLs (20 mm in diameter) were collected consecutively in Shinshu University Hospital from November 2011 to November 2014. The definition of PPLs are generally considered as lesions in the peripheral one-third of the lung. The selection criteria for PPL included PPLs that were invisible or unlikely to be detected by X-ray fluoroscopy.

Exclusion criteria

Exclusion criteria: Negative CT-bronchus sign. No complete data (e.g. no procedure time) Lesion size was bigger than 20mm.

Design outcomes

Primary

Measure	Time frame
Improving diagnostic yield.	—

Secondary

Measure	Time frame
CT-dose index Examination time (Whole procedure time, times at which the first CT scan, and first biopsy)	—

Countries

Japan

Contacts

Public ContactMasanori Yasuo

Shinshu University School of Medicine The First Department of Internal Medicine

yasumasa@shinshu-u.ac.jp0263-37-2631

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026