PRONE POSITIONING AND SPONTANEOUS BREATHING: A FEASIBILITY STUDY

PRONE POSITIONING AND SPONTANEOUS BREATHING: A FEASIBILITY STUDY - The PROSE study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032462

Enrollment

Registered

2018-05-30

Start date

2019-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute respiratory distress syndrome

Interventions

prone positioning with and without muscle paralysis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with moderate-to-severe ARDS as per the Berlin definition (PaO2/FiO2 < 200 mmHg)

Exclusion criteria

Exclusion criteria: Contraindication for prone positioning

Design outcomes

Primary

Measure	Time frame
the strength of spontaneous breathing	—

Secondary

Measure	Time frame
Esophageal pressure, electrical activation of the diaphragm,lung volume, cytokines	—

Countries

Japan,North America,South America

Contacts

Public ContactAkinori Uchiyama

Osaka University Department of Anesthesiology and Intensive Care Medicine

auchiyama@hp-icu.med.osaka-u.ac.jp+81-6-6879-5820

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026