Adults with high normal and impaired fasting glucose (fasting plasma glucose, 100-125 mg/dl)
Conditions
Interventions
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: (1)Adult aged from 20 y to 65 y (2)Subjects with fasting glucose from 100 to 125 mg/dL (3)Subjects can consume test foods, and record life diaries and meal diaries (4)Subjects who have given written informed consent prior to study.
Exclusion criteria
Exclusion criteria: (1)Subjects diagnosed with diabetes mellitus (2)Subjects taking drug related diabetes mellitus (3)Subjects who have history or symptom of cardiovascular disease or cerebrovascular disease (4)Subjects who have symptom of liver, kidney or respiratory disease, endocrine disorder, metabolic disorder, organ disorder, gout, rheumatism, autoimmune disease, allergy disease, mental disorder, cancer, infection disease, or other diseases (5)Subjects who have a history of resection of gastrointestinal tract (6)Subjects having thyroid deficiency (7)Heavy drinker (over 30g per day) (8)Subjects who have donated over 200 mL of blood within the last one month prior to the current study or over 400 mL of blood within the last three months prior to the study (9)Subjects who have severe anemia (Hb <=7g/dL) (10)Subjects who have food allergies for test foods (11)Subjects who are planned to participate in other clinical study during current study (12)Subjects who are judged to be inappropriate for the study by the medical doctor or investigator for other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dose-response assessment based on concentration of gastrointestinal hormone(tAUC, iAUC, C-max). | — |
Secondary
| Measure | Time frame |
|---|---|
| Dose-response assessment based on concentration of insulin and glucose(tAUC, iAUC, C-max). | — |
Countries
Japan
Contacts
Public ContactAya Yanagimoto
Kao Corporation Biological Science Research laboratories
Outcome results
None listed