Diabetes mellitus (DM) patients complicated with heart failure preserved ejection fraction (HFpEF)
Conditions
Interventions
If blood glucose management with patients who were administrated with DPP4 inhibitor were more bad, strict diet exercise therapy is performed and DPP4 inhibitor is continued. DPP4 inhibitors or SGLT
Sponsors
Toho University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Outpatients with DM and HFpEF of NHYA classification of I - III Medications (including DPP4 inhibitor) did not changed of dosage before 4 weeks from examincation start Blood glucose management were worsening and patients who need to strict diet/exercise therapy or change medication.
Exclusion criteria
Exclusion criteria: Pregnancy, breast-feeding, patients who may be pregnant, and patients who want pregnancy during the examination Patients who may be thought to worse blood glucose management with the protocol of this examination. Patients who are received with DPP 4 inhibitor, once a week. Patients with moderate or severe renal impairment (less than eGFR 45) Patients with severe hepatic impairment (Child-Pugh classification C) Patients who were judged inappropriate as subjects of this examination by investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence or absence of total/cardiovascular death, re-hospitalization of HF and worsening of DM | — |
Countries
Japan
Contacts
Public ContactShunsuke Kiuchi
Toho University Omori Medical Center Department of Cardiovascular Medicine
Outcome results
None listed