The efficacy of the Quadratus Lumborum Block anterior approach for the postoperative recovery after Total Hip Arthroplasty. A single-center, double-blinded, randomized controlled trial.

The efficacy of the Quadratus Lumborum Block anterior approach for the postoperative recovery after Total Hip Arthroplasty. A single-center, double-blinded, randomized controlled trial. - The efficacy of the Quadratus Lumborum Block anterior approach for the postoperative recovery after Total Hip Arthroplasty. A single-center, double-blinded, randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032255

Enrollment

140

Registered

2018-04-15

Start date

2018-04-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip osteoarthritis

Interventions

Injecting 0.25% levobupivacaine 30ml under ultrasound-guided Quadratus Lumborum Block anterior approach. Injecting normal saline under ultrasound-guided Quadratus Lumborum Block anterior approach.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Age over 20 years. (2)Scheduled to unilateral total hip arthroplasty. (3)ASA-PS1-2 (4)Written informed consent of this study.

Exclusion criteria

Exclusion criteria: (1)Revision cases. (2)Dysfunction of liver and kidney. (3)Coagulopathy. (4)BMI>35 (5)Strong opioid user such as morphine or fentanyl (6)Allergies to study drugs and their components (7)Dementia. (8)Cases judged to inappropriate by the researchers. For instance, cases where the patient has undergone other femoral surgeries such as intramedullary nailing.

Design outcomes

Primary

Measure	Time frame
Quality of Recovery 40 score 24 hours after surgery.	—

Secondary

Measure	Time frame
1)Fentanyl consumption until 24 hours after surgery, 2)Number of times of use IV-PCA, 3)Pain at rest and effort on postoperative day1, 2(VAS), 4)Post operative nausea and vomit, 5)Intraoperative consumption of fentanyl, 6)Duration of first use of PCA, 7)Intraoperative consumption of remifentanil, 8)The frequency and dose of other analgesic requirements(i.e, flurbiprofen axetil of diclofenac), 9)The time of first ambulation, 10)The manual muscle test (MMT) results for the quadriceps muscle during day 1 of postoperative rehabilitation, 11)Perioperative complications related to surgical or anesthetic procedures (i.e, wound infection, bleeding, dislocation, reoperation, nerve injury, hypotension, or falling), 12)Days in hospital	—

Measure

Time frame

1)Fentanyl consumption until 24 hours after surgery, 2)Number of times of use IV-PCA, 3)Pain at rest and effort on postoperative day1, 2(VAS), 4)Post operative nausea and vomit, 5)Intraoperative consumption of fentanyl, 6)Duration of first use of PCA, 7)Intraoperative consumption of remifentanil, 8)The frequency and dose of other analgesic requirements(i.e, flurbiprofen axetil of diclofenac), 9)The time of first ambulation, 10)The manual muscle test (MMT) results for the quadriceps muscle during day 1 of postoperative rehabilitation, 11)Perioperative complications related to surgical or anesthetic procedures (i.e, wound infection, bleeding, dislocation, reoperation, nerve injury, hypotension, or falling), 12)Days in hospital

—

Countries

Japan

Contacts

Public ContactMasaru Kikuchi

Yokohama City University hospital Anesthesiology

kikutyqdo1009@gmail.com045-787-2918

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026