Autistic spectrum disorder (ASD)
Conditions
Interventions
fMRI measurements during the task of forgiveness and neuropsychological test batteries
Sponsors
Hamamatsu University School of medicine Department of Biofunctional Imaging
Hamamatsu Medical Photonics Foundation Hamamatsu Photonics K.K.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1: Participants aged 20 to 45 (TD persons and ASD males) and 65-85 (elderly persons) 2: right-handedness 3: Individuals who are consent to participate in this study 4:Individuals who have no history of psychiatric disease (both TD and elderly persons) 5:Individuals who are already diagnosed as ASD (ASD males)
Exclusion criteria
Exclusion criteria: 1:(both TD and TO)individuals who have a history of traumatic brain injury with an unconsciousness lasting more than 5 min. 2:(both TD and TO)individuals who have a history of organic brain disease 3:(both TD and TO)individuals who have a history of psychiatric disease 4:(both TD and TO)individuals who have a history of substance dependence 5:(both TD and TO)individuals who are taking central nervous system stimulants 6:(both TD and TO)individuals who have a history of disorders of consciousness and /or seizure 7:(both TD and TO)individuals who have a chronic headache 8:(ASD)individuals who are on medication on the day for MRI measurement 9:(ALL)Individuals who have a risk for MRI scan (1)Individuals who had surgery to insert a pacemaker (2)individuals who had a metallic artificial cardiac valve replacement (3)individuals who insert an artificial inner ear and/or an artificial inner ossicle (4)individuals who use an equipment for deep brain stimulation and/or transcutaneous electrical nerve stimulation (5)Individuals who mount an electrical bone growth stimulator. (6)individuals who use an injection pump (7)individuals who insert an artificial eye body which mounted by magnetic force and insert fake tooth which remove its magnetic parts (8)It takes less than 2 months since a magnetic stent is inserted into a coronary artery etc (9)Intracephalic aneurysm clip and/or coil remains (10)individuals who have any other metals in their body (11)individuals who are suffering from claustrophobia (12)individuals who have tattoos 10: (ALL)individuals whom a researcher does not decide to suit to participate in
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain activation (BOLD signal changes) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1: Evaluation of generosity by dictator game 2: Character analysis by NEO-FFI (NEO Five-Factor Inventory) 3: Scale of J-PAM (Proclivity to Apologize Measure) 4: Scale of J-TRIM (Transgression-Related Interpersonal Motivations) 5: Scale of J-TFS (Trait Forgivingness Scale) 6:IQ from WAIS-III 7: Autistic Quotient from AQ test 8: Brain volumes processed by VBM | — |
Countries
Japan
Contacts
Public ContactHirotoshi Hiraishi
Hamamatsu University School of medicine Department of Biofunctional Imaging
Outcome results
None listed