Identification of Predictive Phenotypes for Development of Asthma in 1-Year-Old Children with Recurrent Wheeze (Phenotyping of wheezing infants; P-WIN study)

Identification of Predictive Phenotypes for Development of Asthma in 1-Year-Old Children with Recurrent Wheeze (Phenotyping of wheezing infants; P-WIN study) - P-WIN study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000032194

Enrollment

250

Registered

2018-04-12

Start date

2018-04-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infantile wheeze

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) At least one episode of wheeze before more than 1 month prior to enrollment 2) Apparent expiratory wheeze persisting for more than 24 h at enrollment

Exclusion criteria

Exclusion criteria: 1) Wheezing due to underlying disease other than asthma (e.g., congenital tracheal stenosis, tracheomalacia, heart diseases) 2) History of respiratory diseases requiring mechanical ventilation during the perinatal period 3) Immunocompromised children

Design outcomes

Primary

Measure	Time frame
Remission of wheezing symptoms 2 years after enrollment	—

Secondary

Measure	Time frame
Physical exam, family history, environment (e.g., pets, passive smoking), infection, allergen sensitization, rhinitis symptoms, and phenotypic classification of wheezing according to drug used Biomarkers by phenotypic class (e.g., serum EDN, periostin, SCCA2)	—

Countries

Japan,Asia(except Japan)

Contacts

Public ContactShinobu Tanimura

Mie National Hospital Department of Clinical Research

mieclinicalresearch@gmail.com059-232-2531

Outcome results