Helicobacter pylori infection
Conditions
Interventions
Vonoprazan 20mg bid Amoxicillin 750mg bid Metronidazole 250mg bid 7 days
Sponsors
Yokohama City University Hospital
Yokohama National University, Yokohama Hodogaya Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Yokohama City University student or Yokohama National University student (2) Urine Helicobacter pylori enzyme-linked immunosorbent assay (u-HpELISA) positive patient which was performed as clinical study: Urine Helicobacter pylori enzyme-linked immunosorbent assay for university student at the health examination and questionnaire based survey(UMIN000032115). (3) A patient who can perform stool antigen test of Helicobacter pylori after 8 weeks from treatment completion. (4)Within 5 months after result notification of u-HpELISA. (5)A patient who give a written informed consent.
Exclusion criteria
Exclusion criteria: (1) A patient with history of Helicobacter pylori eradication. (2) Patients allergic to penicillin. (3) Past history of allergy for the drugs used in this study. (4) Pregnancy. (5) Lactation. (6) A patient with brain and spinal cord disease. (7) A patient with infectious mononucleosis. (8) Severe liver dysfunction, severe renal dysfunction, severe heart dysfunction. (9) Patient who is disqualified for the study by physicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate assessed by stool antigen test of Helicobacter pylori more than 8 weeks after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event evaluated by side effect questionnaire filled by patients | — |
Countries
Japan
Contacts
Public ContactSoichiro Sue
Yokohama City University Hospital Gastroenterology
Outcome results
None listed