The effect of olfactory training using flavor enhanced food on cognitive function of elderly people.

The effect of olfactory training using flavor enhanced food on cognitive function of elderly people. - The effect of olfactory training using flavor enhanced food on cognitive function of elderly people.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032059

Enrollment

Registered

2018-04-21

Start date

2018-04-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community-dwelling elderly people

Interventions

Interventions group: Elderly people are asked to intake flavor enhanced food (test food), sniffing with a conscious awareness of the flavor. They are asked to repeat this training once a day during 12

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: [1]Males and females aged more than 65 years. [2]Individuals whose written informed consent has been obtained.

Exclusion criteria

Exclusion criteria: [1]Individuals who have a history of mental or cerebrovascular diseases. [2]Individuals who use medicines which may affect central nerve. [3]Individuals who regularly visit otorhinolaryngology. [4]Individuals who regularly intake supplements or healthy foods which may affect cognitive function. [5]Individuals who regularly intake medicines for pollen allergy. [6]Individuals whose score of MMSE test at screening are below 26. [7]Individuals who have allergy of milk, wheat or dried bonito flakes. [8]Individuals judged inappropriate by blood test at screening. [9]Individuals who have a history of drug or alcohol dependence. [10]Individuals who participate or will participate clinical studies. [11]Individuals judged inappropriate for the trial by the principal.

Design outcomes

Primary

Measure	Time frame
Cognitive function [1]Word fluency test, [2]TMT-A,B ([1]~[2] Before and after 12-week ingestion)	—

Secondary

Measure	Time frame
Secondary outcomes [1]WHO-5, [2]Olfactory identification test, [3]Questionnaire about diet and mood ([1]~[3] Before and 12-week ingestion) Safety [1]Doctor's questions [2]Body weight (BMI) [3]Blood pressure and pulse rate [4]Blood test, blood biochemical test, and urine analysis ([1]~[3] Before and after 12-week ingestion, [4]Screening and after 12-week ingestion) *Other indexes [1]Doctor's questions [2]Body height and weight (BMI) [3]Blood pressure and pulse rate [4]Blood test, blood biochemical test, and urine analysis [5]MMSE test [6]Subject's diary ([1]~[5]Screening, [6]During 12-week ingestion)	—

Measure

Time frame

*Secondary outcomes [1]WHO-5, [2]Olfactory identification test, [3]Questionnaire about diet and mood ([1]~[3] Before and 12-week ingestion) *Safety [1]Doctor's questions [2]Body weight (BMI) [3]Blood pressure and pulse rate [4]Blood test, blood biochemical test, and urine analysis ([1]~[3] Before and after 12-week ingestion, [4]Screening and after 12-week ingestion) *Other indexes [1]Doctor's questions [2]Body height and weight (BMI) [3]Blood pressure and pulse rate [4]Blood test, blood biochemical test, and urine analysis [5]MMSE test [6]Subject's diary ([1]~[5]Screening, [6]During 12-week ingestion)

—

Countries

Japan

Contacts

Public ContactYoshika Komori

KSO Corporation Chairman & CEO

yoshi@kso.co.jp03-3452-7733

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026